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nouna proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)type of:
Definition that contains tnf
- infliximab an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis
- arava an anti-TNF compound (trade name Arava) that is given orally; can slow the progression of rheumatoid arthritis by slowing the proliferation of white blood cells which reduces inflammation in the synovium
- leflunomide an anti-TNF compound (trade name Arava) that is given orally; can slow the progression of rheumatoid arthritis by slowing the proliferation of white blood cells which reduces inflammation in the synovium
- enbrel a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis
- remicade an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis
- etanercept a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis
- anti-tnf compound a class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints